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Parent [Member] Work-in-process Inventory, Work in Process, Net of Reserves Revenue recognition Revenue from Contract with Customer [Text Block] Debt instrument, covenant, net leverage ratio, maximum Debt Instrument, Covenant, Net Leverage Ratio, One Debt Instrument, Covenant, Net Leverage Ratio, One Segment Reporting [Abstract] Term Loan Facility Term Loan Facility [Member] Term loan dated December 2013. Percentage of original principal amount required to repay during the third year Percentage of Original Principal Amount Required to Repay During the Third Year The rate of interest that was being paid on the original debt issue that is to repay in the third year. Upon the occurrence of a change in control Debt Instrument, Redemption, Period Two [Member] Forecast Forecast [Member] Taxes paid for share-based compensation activity Payment, Tax Withholding, Share-Based Payment Arrangement Total liabilities and stockholders' equity Liabilities and Equity Raw materials and supplies Inventory, Raw Materials and Supplies, Net of Reserves Eurocurrency Eurodollar [Member] Amortization of deferred financing costs Amortization of Debt Issuance Costs Long-term Debt, Type [Axis] Long-Term Debt, Type [Axis] Goodwill [Roll Forward] Goodwill [Roll Forward] Debt instrument, covenant, net leverage ratio, adjustment Debt Instrument, Covenant, Net Leverage Ratio, Two Debt Instrument, Covenant, Net Leverage Ratio, Two Dilutive securities-equity awards (in shares) Incremental Common Shares Attributable to Dilutive Effect of Share-Based Payment Arrangements Net income (loss) per common share Earnings Per Share, Diluted [Abstract] Non-U.S. Government Non-US [Member] Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] AOCI Attributable to Parent, Net of Tax [Roll Forward] AOCI Attributable to Parent, Net of Tax [Roll Forward] Reconciliation of Operating Profit (Loss) from Segments to Consolidated Reconciliation of Operating Profit (Loss) from Segments to Consolidated [Table Text Block] Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Fair Value, Inputs, Level 2 Fair Value, Inputs, Level 2 [Member] Prior to August 15, 2023 Debt Instrument, Redemption, Period One [Member] Current Fiscal Year End Date Current Fiscal Year End Date Vesting [Axis] Vesting [Axis] Finite-Lived Intangible Assets [Line Items] Finite-Lived Intangible Assets [Line Items] Diluted (in dollars per share) Net income per share - diluted (in dollars per share) Earnings Per Share, Diluted Intangible assets, net Intangible Assets, Net (Excluding Goodwill) Tranche Two Share-Based Payment Arrangement, Tranche Two [Member] Award vesting period Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Consolidation Items [Axis] Consolidation Items [Axis] Total current liabilities Liabilities, Current Milestone Payment Three Milestone Payment Three [Member] Milestone Payment Three 3.875% Senior Unsecured Notes due 2028 Senior Unsecured Notes Due August 2028 [Member] Senior Unsecured Notes Due August 2028 Total contract development and manufacturing Revenues Operating Lease, Lease Income And Revenue From Contract With Customer, Excluding Assessed Tax Operating Lease, Lease Income And Revenue From Contract With Customer, Excluding Assessed Tax Revenue, remaining performance obligation, amount Revenue, Remaining Performance Obligation, Amount Fair Values Derivatives, Balance Sheet Location, by Derivative Contract Type [Table] Fair Values Derivatives, Balance Sheet Location, by Derivative Contract Type [Table] Commitment fee percentage Line of Credit Facility, Commitment Fee Percentage Schedule of Derivative Instruments Schedule of Derivative Instruments [Table Text Block] Other income (expense): Nonoperating Income (Expense) [Abstract] Percentage of original principal amount required to repay remaining year Percentage of Original Principal Amount Required to Repay Remaining Years The rate of interest that was being paid on the original debt issue that is to repay in remaining years. Asset Derivatives Derivative Asset, Subject to Master Netting Arrangement, before Offset Milestone Payment Four Milestone Payment Four [Member] Milestone Payment Four Entity Address, Address Line One Entity Address, Address Line One Beginning of period End of period Contract with Customer, Liability Product and Service [Axis] Products and Services [Axis] Product and Service [Axis] Unbilled Unbilled Contracts Receivable Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Interest expense Interest Expense Derivative Instruments and Hedging Activities Disclosure [Abstract] Derivative Instruments and Hedging Activities Disclosure [Abstract] Credit Facility [Axis] Credit Facility [Axis] Inventories, net Inventory Disclosure [Text Block] Reconciliation of cash and cash equivalents and restricted cash at June 30, 2022 and December 31, 2021: Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents [Abstract] Cash and Cash Equivalents [Domain] Cash and Cash Equivalents [Domain] Equity [Abstract] Inventory Disclosure [Abstract] Inventory Disclosure [Abstract] Entity Tax Identification Number Entity Tax Identification Number Derivatives, Fair Value [Line Items] Derivatives, Fair Value [Line Items] Asset Acquisition [Line Items] Asset Acquisition [Line Items] Asset acquisition, international royalty percentage Asset Acquisition, International Gross Profit Royalty Percentage Asset Acquisition, International Gross Profit Royalty Percentage Disaggregation of Revenue Disaggregation of Revenue [Table Text Block] Revenue from Contract with Customer [Abstract] Revenue from Contract with Customer [Abstract] Unobservable Input Reconciliation [Roll Forward] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward] Net change in cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Amended Credit Agreement Amended Credit Agreement [Member] Amended credit agreement dated October 15, 2018. Business combination, contingent consideration, liability, measurement input Business Combination, Contingent Consideration, Liability, Measurement Input Entity Central Index Key Entity Central Index Key Measurement Frequency [Axis] Measurement Frequency [Axis] Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets by Major Class [Axis] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Comprehensive Income (Loss) Comprehensive Income (Loss) [Table Text Block] Income Taxes [Table] Income Taxes [Table] Income Taxes Measurement Input Type [Axis] Measurement Input Type [Axis] City Area Code City Area Code ASSETS Assets [Abstract] Unamortized debt issuance costs Debt Issuance Costs, Noncurrent, Net Long-term Debt, Type [Domain] Long-Term Debt, Type [Domain] Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Debt Instrument, Redemption, Period [Axis] Debt Instrument, Redemption, Period [Axis] Cash flows used in financing activities: Net Cash Provided by (Used in) Financing Activities [Abstract] Debt instrument, covenant, net leverage ratio rolling period Debt Instrument, Covenant, Net Leverage Ratio Rolling Period Debt Instrument, Covenant, Net Leverage Ratio Rolling Period Supplemental information on non-cash investing and financing activities: Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Share-based compensation expense Share-Based Payment Arrangement, Noncash Expense Variable Rate [Axis] Variable Rate [Axis] Other liabilities Other Liabilities, Noncurrent Purchases of property, plant and equipment Payments to Acquire Property, Plant, and Equipment Research and development Research and Development Expense [Member] Disaggregation of Revenue [Line Items] Disaggregation of Revenue [Line Items] Weighted Average Weighted Average [Member] Basic and Diluted Net Income per Share Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Cash proceeds excess amount from dispositions of property or casualty events subject to certain reinvestment right Cash Proceeds Excess Amount from Dispositions of Property or Casualty Events Subject to Certain Reinvestment Right The cash proceeds in excess during the term of the Senior Secured Credit Facility from certain dispositions of property or from casualty events involving their property, subject to certain reinvestment rights. Cost of product sales Cost of Sales [Member] Customer [Domain] Customer [Domain]