Organization, Consolidation and Presentation of Financial Statements [Abstract] Number of categories of public health threats Number Of Categories Of Public Health Threats Refers to the number of categories of public health threats. Number of revenue generating products Number Of Revenue Generating Products Refers to the number of revenue generating products. Number of operating segments Number of Operating Segments Fair Value Disclosures [Abstract] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Valuation Approach and Technique [Axis] Valuation Approach and Technique [Axis] Valuation Approach and Technique [Domain] Valuation Approach and Technique [Domain] Discounted cash flow Valuation Technique, Discounted Cash Flow [Member] Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Domain] Fair Value Hierarchy and NAV [Domain] Fair Value, Inputs, Level 3 Fair Value, Inputs, Level 3 [Member] Measurement Frequency [Axis] Measurement Frequency [Axis] Measurement Frequency [Domain] Measurement Frequency [Domain] Fair Value, Recurring Fair Value, Recurring [Member] Measurement Input Type [Axis] Measurement Input Type [Axis] Measurement Input Type [Domain] Measurement Input Type [Domain] Discount rate Measurement Input, Discount Rate [Member] Probability of payment Measurement Input, Probability of Payment [Member] Measurement Input, Probability of Payment [Member] Statistical Measurement [Axis] Statistical Measurement [Axis] Statistical Measurement [Domain] Statistical Measurement [Domain] Minimum Minimum [Member] Maximum Maximum [Member] Weighted Average Weighted Average [Member] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items] Fair value, measurement with unobservable inputs reconciliation, recurring basis, liability value Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value Business combination, contingent consideration, liability, measurement input Business Combination, Contingent Consideration, Liability, Measurement Input Derivative Instruments and Hedging Activities Disclosure [Abstract] Fair Values Derivatives, Balance Sheet Location, by Derivative Contract Type [Table] Fair Values Derivatives, Balance Sheet Location, by Derivative Contract Type [Table] Derivative Instrument [Axis] Derivative Instrument [Axis] Derivative Contract [Domain] Derivative Contract [Domain] Interest rate swaps Interest Rate Swap [Member] Hedging Designation [Axis] Hedging Designation [Axis] Hedging Designation [Domain] Hedging Designation [Domain] Designated as Hedging Instrument Designated as Hedging Instrument [Member] Balance Sheet Location [Axis] Balance Sheet Location [Axis] Balance Sheet Location [Domain] Balance Sheet Location [Domain] Other Current Assets Other Current Assets [Member] Other Assets Other Assets [Member] Other Current Liabilities Other Current Liabilities [Member] Other Liabilities Other Liabilities [Member] Derivatives, Fair Value [Line Items] Derivatives, Fair Value [Line Items] Asset Derivatives Derivative Asset, Fair Value, Gross Asset Liability Derivatives Derivative Liability, Fair Value, Gross Liability Debt Disclosure [Abstract] Schedule of Debt Schedule of Debt [Table Text Block] Revenue from Contract with Customer [Abstract] Disaggregation of Revenue Disaggregation of Revenue [Table Text Block] Rollforward of Contract Liabilities Contract with Customer, Asset and Liability [Table Text Block] Schedule of Accounts Receivable, Net Schedule of Accounts Receivable, Net [Table Text Block] Schedule of Accounts Receivable, Net [Table Text Block] Reconciliation of Liabilities Measured at Fair Value Using Significant Unobservable Inputs (Level 3) Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block] Fair Value Measurement Inputs and Valuation Techniques Fair Value Measurement Inputs and Valuation Techniques [Table Text Block] Revenue, remaining performance obligation, amount Revenue, Remaining Performance Obligation, Amount Deferred costs, current Deferred Costs, Current Business Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Disaggregation of Revenue [Table] Disaggregation of Revenue [Table] Products and Services [Axis] Product and Service [Axis] Product and Service [Domain] Product and Service [Domain] Product sales, net Product [Member] Contract development and manufacturing services Contract Manufacturing [Member] Revenue earned during the period arising from manufacturing sale under the terms of a contract. Contracts and grants Contracts and Grants [Member] Amount of revenue earned from products sold or services provided under the terms of a contract, including, but not limited to, government contracts and grants. Geographical [Axis] Geographical [Axis] Geographical [Domain] Geographical [Domain] U.S. Government UNITED STATES Non-U.S. Government Non-US [Member] Disaggregation of Revenue [Line Items] Disaggregation of Revenue [Line Items] Total revenues Revenue from Contract with Customer, Excluding Assessed Tax Earnings Per Share [Abstract] Net loss per share Earnings Per Share [Text Block] Leases [Abstract] Leases Lessee, Operating Leases [Text Block] Leases Lessee, Finance Leases [Text Block] Derivative Instruments and Hedging Activities Disclosure Derivative Instruments and Hedging Activities Disclosure [Text Block] Change in Contract With Customer, Liability [Roll Forward] Change in Contract With Customer, Liability [Roll Forward] Change in Contract With Customer, Liability [Roll Forward] Beginning of period Contract with Customer, Liability Deferral of revenue Contract with Customer, Liability, Additions Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable recorded during the current reporting period. Revenue recognized Contract with Customer, Liability, Revenue Recognized End of period Stockholders' Equity Note [Abstract] Share-based compensation Stockholders' Equity Note Disclosure [Text Block] Operating lease cost: Lease, Cost [Abstract] Amortization of right-of-use assets Finance Lease, Right-of-Use Asset, Amortization Interest on lease liabilities Finance Lease, Interest Expense Total operating lease cost Lease, Cost Schedule of Derivative Instruments Schedule of Derivative Instruments [Table Text Block] Schedule of Derivative Instruments in Statement of Financial Position, Fair Value Schedule of Derivative Instruments in Statement of Financial Position, Fair Value [Table Text Block] Derivative Instruments, Gain (Loss) Derivative Instruments, Gain (Loss) [Table Text Block] Schedule of Long-term Debt Instruments [Table] Schedule of Long-term Debt Instruments [Table] Credit Facility [Axis] Credit Facility [Axis] Credit Facility [Domain] Credit Facility [Domain] Senior secured credit agreement - Term loan due 2023 Term Loan Facility [Member] Term loan dated December 2013. Senior secured credit agreement - Revolver loan due 2023 Revolving Credit Facility [Member] Debt Instrument [Axis] Debt Instrument [Axis] Debt Instrument, Name [Domain] Debt Instrument, Name [Domain] 2.875% Convertible Senior Notes due 2021 Convertible Senior Notes Due 2021 [Member] Convertible Senior Notes Due 2021 [Member] Other Other Long Term Debt Facility [Member] Other Long Term Debt Facility [Member] Debt Instrument [Line Items] Debt Instrument [Line Items] Long-term debt Long-term Debt Current portion of long-term debt, net of debt issuance costs Long-term Debt, Current Maturities Unamortized debt issuance costs Debt Issuance Costs, Noncurrent, Net Non-current portion of debt Long-term Debt, Excluding Current Maturities Stated percentage Debt Instrument, Interest Rate, Stated Percentage Goodwill and Intangible Assets Disclosure [Abstract] Schedule of Finite-Lived Intangible Assets Schedule of Finite-Lived Intangible Assets [Table Text Block] Accounting Policies [Abstract] Money market funds Money Market Funds, at Carrying Value Property Plant and Equipment Income Statement Disclosures [Abstract] Property, plant and equipment Property, Plant and Equipment [Table Text Block] Schedule of Business Acquisitions, by Acquisition [Table] Schedule of Business Acquisitions, by Acquisition [Table] Business Acquisition [Axis] Business Acquisition [Axis] Business Acquisition, Acquiree [Domain] Business Acquisition, Acquiree [Domain] Raxibacumab Raxibacumab [Member] Raxibacumab [Member] Business Acquisition [Line Items] Business Acquisition [Line Items] Change in amount of contingent consideration, liability Business Combination, Contingent Consideration Arrangements, Change in Amount of Contingent Consideration, Liability Amortization Amortization of Intangible Assets Weighted average amortization period Acquired Finite-lived Intangible Assets, Weighted Average Useful Life Goodwill Goodwill Statement of Financial Position [Abstract] ASSETS Assets [Abstract] Current assets: Assets, Current [Abstract] Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Restricted cash Restricted Cash, Current Accounts receivable, net Accounts Receivable, after Allowance for Credit Loss, Current Inventories Inventory, Net Income tax receivable, net Income Taxes Receivable, Current Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Total current assets Assets, Current Property, plant and equipment, net Property, Plant and Equipment, Net Intangible assets, net Intangible Assets, Net (Excluding Goodwill) In-process research and development In Process Research And Development Carrying amount of purchased research and development assets acquired in a business combination that have an indefinite life until completion or abandonment of the associated research and development efforts. Deferred tax assets, net Deferred Income Tax Assets, Net Other assets Other Assets, Noncurrent Total assets Assets LIABILITIES AND STOCKHOLDERS' EQUITY Liabilities and Equity [Abstract] Current liabilities: Liabilities, Current [Abstract] Accounts payable Accounts Payable, Current Accrued expenses Accrued Liabilities, Current Debt, current portion Employee-related Liabilities, Current Debt, current portion Notes Payable, Current Other current liabilities Other Liabilities, Current Total current liabilities Liabilities, Current Contingent consideration, net of current portion Business Combination, Contingent Consideration, Liability, Noncurrent Debt, net of current portion Deferred tax liability Deferred Income Tax Liabilities, Net Contract liabilities, net of current portion Contract with Customer, Liability, Noncurrent Other liabilities Other Liabilities, Noncurrent Total liabilities Liabilities Stockholders' equity: Stockholders' Equity, Including Portion Attributable to Noncontrolling Interest [Abstract] Preferred stock, $0.001 par value; 15.0 shares authorized, no shares issued or outstanding Preferred Stock, Value, Issued Common stock, $0.001 par value; 200.0 shares authorized, 53.5 and 53.0 shares issued; 52.3 and 51.7 shares outstanding, respectively Common Stock, Value, Issued Treasury stock, at cost, 1.2 common shares Treasury Stock, Value Additional paid-in capital Additional Paid in Capital Accumulated other comprehensive loss, net Accumulated Other Comprehensive Income (Loss), Net of Tax Retained earnings Retained Earnings (Accumulated Deficit) Total stockholders' equity Stockholders' Equity Attributable to Parent Total liabilities and stockholders' equity Liabilities and Equity Statement of Cash Flows [Abstract] Cash flows provided by operating activities: Net Cash Provided by (Used in) Operating Activities [Abstract] Net income Net Income (Loss) Attributable to Parent Adjustments to reconcile net loss to net cash provided by operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Share-based compensation expense Share-based Payment Arrangement, Noncash Expense Depreciation and amortization Depreciation, Depletion and Amortization Amortization of deferred financing costs Amortization of Debt Issuance Costs Deferred income taxes Deferred Income Tax Expense (Benefit) Change in fair value of contingent consideration, net Change In Fair Value Of Contingent Consideration Fair value measurement of contingent value rights and contingent purchase considerations granted under purchase agreements. Other Other Noncash Income (Expense) Changes in operating assets and liabilities: Increase (Decrease) in Operating Capital [Abstract] Accounts receivable Increase (Decrease) in Accounts Receivable Inventories Increase (Decrease) in Inventories Prepaid expenses and other assets Increase (Decrease) in Prepaid Expense and Other Assets Accounts payable Increase (Decrease) in Accounts Payable Accrued expenses Increase (Decrease) in Accrued Liabilities Accrued compensation Increase (Decrease) in Employee Related Liabilities Contract liabilities Increase (Decrease) in Contract with Customer, Liability Net cash provided by operating activities: Net Cash Provided by (Used in) Operating Activities Cash flows used in investing activities: Net Cash Provided by (Used in) Investing Activities [Abstract] Purchases of property, plant and equipment and other Payments to Acquire Property, Plant, and Equipment Net cash used in investing activities: Net Cash Provided by (Used in) Investing Activities Cash flows used in financing activities: Net Cash Provided by (Used in) Financing Activities [Abstract] Proceeds from revolving credit facility Proceeds from Lines of Credit Principal payments on revolving credit facility Repayments of Lines of Credit Principal payments on term loan facility Repayments of Medium-term Notes Proceeds from issuance of common stock upon exercise of stock options Proceeds from Stock Options Exercised Taxes paid on behalf of employees for equity activity Payment, Tax Withholding, Share-based Payment Arrangement Contingent consideration payments Payment for Contingent Consideration Liability, Financing Activities Net cash used in financing activities: Net Cash Provided by (Used in) Financing Activities Effect of exchange rate changes on cash, cash equivalents and restricted cash Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents Net increase in cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Cash, cash equivalents and restricted cash at beginning of period Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents Cash, cash equivalents and restricted cash at end of period Supplemental disclosure of cash flow information: Supplemental Cash Flow Information [Abstract] Cash paid during the period for interest Interest Paid, Excluding Capitalized Interest, Operating Activities Cash paid during the period for income taxes Income Taxes Paid Supplemental information on non-cash investing and financing activities: Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Purchases of property, plant and equipment unpaid at period end Capital Expenditures Incurred but Not yet Paid Reconciliation of cash and cash equivalent and restricted cash Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents [Abstract] Total cash, cash equivalents and restricted cash Derivative Instruments and Hedging Activities Disclosures [Table] Derivative Instruments and Hedging Activities Disclosures [Table] Derivative Instruments and Hedging Activities Disclosures [Line Items] Derivative Instruments and Hedging Activities Disclosures [Line Items] Net deferred losses from accumulated other comprehensive loss Cash Flow Hedge Gain (Loss) to be Reclassified within Twelve Months 2017 Credit Agreement Credit Agreement [Member] Credit agreement dated September 2017. Amended Credit Agreement Amended Credit Agreement [Member] Amended credit agreement dated October 15, 2018. Variable Rate [Axis] Variable Rate [Axis] Variable Rate [Domain] Variable Rate [Domain] Eurocurrency Eurodollar [Member] Federal Funds Rate Fed Funds Effective Rate Overnight Index Swap Rate [Member] Base Rate Base Rate [Member] Current borrowing capacity Line of Credit Facility, Current Borrowing Capacity Debt instrument, basis spread on variable rate Debt Instrument, Basis Spread on Variable Rate Commitment fee percentage Line of Credit Facility, Commitment Fee Percentage Percentage of original principal amount required to repay in the first two years Percentage of Original Principal Amount Required to Repay in First Two Years The rate of interest that was being paid on the original debt issue that is to repay in the first two years. Percentage of original principal amount required to repay during the third year Percentage of Original Principal Amount Required to Repay During the Third Year The rate of interest that was being paid on the original debt issue that is to repay in the third year. Percentage of original principal amount required to repay remaining year Percentage of Original Principal Amount Required to Repay Remaining Years The rate of interest that was being paid on the original debt issue that is to repay in remaining years. Cash proceeds excess amount from dispositions of property or casualty events subject to certain reinvestment right Cash Proceeds Excess Amount from Dispositions of Property or Casualty Events Subject to Certain Reinvestment Right The cash proceeds in excess during the term of the Senior Secured Credit Facility from certain dispositions of property or from casualty events involving their property, subject to certain reinvestment rights. Debt covenant, consolidated debt service coverage ratio, minimum Debt Instrument, Covenant, Debt Service Coverage Ratio Debt Instrument, Covenant, Debt Service Coverage Ratio Debt instrument, covenant, net leverage ratio through June 30, 2019 Debt Instrument, Covenant, Net Leverage Ratio, One Debt Instrument, Covenant, Net Leverage Ratio, One Debt instrument, covenant, net leverage ratio to September 30, 2019 Debt Instrument, Covenant, Net Leverage Ratio, Two Debt Instrument, Covenant, Net Leverage Ratio, Two Debt instrument, covenant, net leverage ratio from October 1, 2019 to September 29, 2020 Debt Instrument, Covenant, Net Leverage Ratio, Three Debt Instrument, Covenant, Net Leverage Ratio, Three Debt instrument, covenant, net leverage ratio rolling period Debt Instrument, Covenant, Net Leverage Ratio Rolling Period Debt Instrument, Covenant, Net Leverage Ratio Rolling Period Debt instrument, covenant, net leverage ratio adjustment period Debt Instrument, Covenant, Net Leverage Ratio Adjustment Period Debt Instrument, Covenant, Net Leverage Ratio Adjustment Period Billed, net Billed Contracts Receivable Unbilled Unbilled Contracts Receivable Total, net Allowance for doubtful accounts receivable Accounts Receivable, Allowance for Credit Loss Basic and Diluted Net Income per Share Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Contingent Consideration Fair Value Disclosures [Text Block] Schedule of Finite-Lived Intangible Assets [Table] Schedule of Finite-Lived Intangible Assets [Table] Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets, Major Class Name [Domain] Finite-Lived Intangible Assets, Major Class Name [Domain] Products Customer relationships Customer Relationships [Member] Contract development and manufacturing services Finite-Lived Intangible Assets [Line Items] Finite-Lived Intangible Assets [Line Items] Amortization period of intangible asset Finite-Lived Intangible Asset, Useful Life Cost Finite-Lived Intangible Assets, Net [Abstract] Intangible assets, gross Finite-Lived Intangible Assets, Gross Finite-lived intangible assets acquired Finite-lived Intangible Assets Acquired Finite-lived intangible assets, accumulated amortization Finite-Lived Intangible Assets, Accumulated Amortization Intangible assets, net Finite-Lived Intangible Assets, Net Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Vesting [Axis] Vesting [Axis] Vesting [Domain] Vesting [Domain] Tranche One Share-based Payment Arrangement, Tranche One [Member] Tranche Two Share-based Payment Arrangement, Tranche Two [Member] Tranche Three Share-based Payment Arrangement, Tranche Three [Member] Award Type [Axis] Award Type [Axis] Award Type [Domain] Award Type [Domain] Stock Options Share-based Payment Arrangement, Option [Member] Restricted Stock Units Restricted Stock Units (RSUs) [Member] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Stock issued or granted during period [Abstract] Shares Granted or Issued, Share-based Payment Arrangement [Abstract] Stock options granted (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Net of Forfeitures Restricted stock units granted (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period Award vesting rights, percentage Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage Award vesting period Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period Statement of Stockholders' Equity [Abstract] Common stock, par value (in dollars per share) Common Stock, Par or Stated Value Per Share Income Tax Disclosure [Abstract] Income taxes Income Tax Disclosure [Text Block] Preferred stock, par value (in dollars per share) Preferred Stock, Par or Stated Value Per Share Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Preferred stock, shares issued (in shares) Preferred Stock, Shares Issued Preferred stock, shares outstanding (in shares) Preferred Stock, Shares Outstanding Common stock, shares authorized (in shares) Common Stock, Shares Authorized Common stock, shares issued (in shares) Common Stock, Shares, Issued Common stock, shares outstanding (in shares) Common Stock, Shares, Outstanding Treasury stock (in shares) Treasury Stock, Shares Debt Debt Disclosure [Text Block] Hedging Relationship [Axis] Hedging Relationship [Axis] Hedging Relationship [Domain] Hedging Relationship [Domain] Cash Flow Hedging Cash Flow Hedging [Member] Income Statement Location [Axis] Income Statement Location [Axis] Income Statement Location [Domain] Income Statement Location [Domain] Interest expense Interest Expense [Member] Cumulative Amount of Gain/(Loss) Recognized in OCI on Derivative Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification, Tax Amount of Gain/(Loss) Reclassified from Accumulated OCI into Income Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, before Tax Effective annual tax rate Effective Income Tax Rate Reconciliation, Percent Discrete tax benefit Share-based Payment Arrangement, Expense, Tax Benefit Cover [Abstract] Document Type Document Type Document Quarterly Report Document Quarterly Report Document Period End Date Document Period End Date Document Transition Report Document Transition Report Entity File Number Entity File Number Entity Registrant Name Entity Registrant Name Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Entity Tax Identification Number Entity Tax Identification Number Entity Address, Address Line One Entity Address, Address Line One Entity Address, City or Town Entity Address, City or Town Entity Address, State or Province Entity Address, State or Province Entity Address, Postal Zip Code Entity Address, Postal Zip Code City Area Code City Area Code Local Phone Number Local Phone Number Title of 12(b) Security Title of 12(b) Security Trading Symbol Trading Symbol Security Exchange Name Security Exchange Name Entity Current Reporting Status Entity Current Reporting Status Entity Interactive Data Current Entity Interactive Data Current Entity Filer Category Entity Filer Category Entity Small Business Entity Small Business Entity Emerging Growth Company Entity Emerging Growth Company Entity Shell Company Entity Shell Company Entity Common Stock, Shares Outstanding (in shares) Entity Common Stock, Shares Outstanding Entity Central Index Key Entity Central Index Key Current Fiscal Year End Date Current Fiscal Year End Date Amendment Flag Amendment Flag Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Property, plant and equipment Property, Plant and Equipment Disclosure [Text Block] Inventory Disclosure [Abstract] Inventories Schedule of Inventory, Current [Table Text Block] Statement [Table] Statement [Table] Equity Components [Axis] Equity Components [Axis] Equity Component [Domain] Equity Component [Domain] $0.001 Par Value Common Stock Common Stock [Member] Additional Paid-In Capital Additional Paid-in Capital [Member] Treasury Stock Treasury Stock [Member] Accumulated Other Comprehensive Loss AOCI Attributable to Parent [Member] Retained Earnings Retained Earnings [Member] Statement [Line Items] Statement [Line Items] Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Balance (in shares) Balance Employee equity plans activity (in shares) Shares Issued, Shares, Share-based Payment Arrangement, after Forfeiture Employee equity plans activity Shares Issued, Value, Share-based Payment Arrangement, after Forfeiture Other comprehensive income Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Balance (in shares) Balance Revenue, remaining performance obligation, expected timing of satisfaction, period Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Period Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Table] Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Table] Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis] Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis] Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items] Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items] Lessee, Lease, Description [Table] Lessee, Lease, Description [Table] Lessee, Lease, Description [Line Items] Lessee, Lease, Description [Line Items] Operating lease, term of contract Lessee, Operating Lease, Term of Contract Operating lease, renewal term Lessee, Operating Lease, Renewal Term Operating lease, termination period Lessee, Operating Lease, Termination Period Lessee, Operating Lease, Termination Period Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Legal Matters and Contingencies [Text Block] Statement of Comprehensive Income [Abstract] Net loss Other comprehensive (loss) income, net of tax: Other Comprehensive Income (Loss), Net of Tax [Abstract] Foreign currency translation Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax Unrealized losses on hedging activities, net of tax Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification and Tax Unrealized losses on pension benefit obligation, net of tax Other Comprehensive (Income) Loss, Defined Benefit Plan, after Tax and Reclassification Adjustment, Attributable to Parent Total other comprehensive (loss) income, net of tax Comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent Basis of presentation Consolidation, Policy [Policy Text Block] Fair value measurements Fair Value Measurement, Policy [Policy Text Block] Recently issued accounting standards New Accounting Pronouncements, Policy [Policy Text Block] Property, Plant and Equipment [Table] Property, Plant and Equipment [Table] Property, Plant and Equipment, Type [Axis] Property, Plant and Equipment, Type [Axis] Property, Plant and Equipment, Type [Domain] Property, Plant and Equipment, Type [Domain] Land and improvements Land and Land Improvements [Member] Buildings, building improvements and leasehold improvements Building and Building Improvements [Member] Furniture and equipment Furniture and Fixtures [Member] Software Computer Software, Intangible Asset [Member] Construction-in-progress Construction in Progress [Member] Property, Plant and Equipment [Line Items] Property, Plant and Equipment [Line Items] Property, Plant and Equipment [Abstract] Property, Plant and Equipment, Net [Abstract] Property, plant and equipment, gross Property, Plant and Equipment, Gross Accumulated depreciation Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Total property, plant and equipment, net Lease, Cost Lease, Cost [Table Text Block] Schedule of Leases Supplemental Balance Sheets Schedule Of Leases Supplemental Balance Sheets [Table Text Block] Schedule Of Leases Supplemental Balance Sheets [Table Text Block] Income Statement [Abstract] Product and Service [Axis] Revenues: Revenues [Abstract] Operating expenses: Operating Expenses [Abstract] Cost of product sales and contract development and manufacturing services Cost of Goods and Services Sold Research and development Research and Development Expense Selling, general and administrative Selling, General and Administrative Expense Amortization of intangible assets Total operating expenses Operating Costs and Expenses Loss from operations Operating Income (Loss) Other (expense) income: Nonoperating Income (Expense) [Abstract] Interest expense Interest Expense Other expense, net Other Nonoperating Income (Expense) Total other expense, net Nonoperating Income (Expense) Loss before provision for income taxes Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Noncontrolling Interest Income tax benefit Income Tax Expense (Benefit) Net loss Net loss per common share Basic (in dollars per share) Earnings Per Share, Basic Diluted (in dollars per share) Earnings Per Share, Diluted Shares used in computing loss per share Earnings Per Share, Basic and Diluted, Other Disclosures [Abstract] Basic (in shares) Weighted Average Number of Shares Outstanding, Basic Diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted Raw materials and supplies Inventory, Raw Materials and Supplies, Net of Reserves Work-in-process Inventory, Work in Process, Net of Reserves Finished goods Inventory, Finished Goods, Net of Reserves Total inventories Unobservable Input Reconciliation [Roll Forward] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward] Balance, beginning of period Change in fair value Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Change In Fair Value Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Change In Fair Value Settlements Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Settlements Balance, end of period Basis of Presentation and Principles of Consolidation Significant Accounting Policies [Text Block] Unrealized losses on hedging activities Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification, Tax Unrealized losses related to foreign currency translations Other Comprehensive Income (Loss), Foreign Currency Translation Gain (Loss) Arising During Period, Tax Inventories Inventory Disclosure [Text Block] Revenue recognition Revenue from Contract with Customer [Text Block] Number of Instruments Number of Interest Rate Derivatives Held Notional Derivative, Notional Amount1 Derivative, Notional Amount1 Operating Leases Lessee, Operating Lease, Liability, Payment, Due [Abstract] Operating lease right-of-use assets Operating Lease, Right-of-Use Asset Operating lease liabilities, current portion Operating Lease, Other Liability, Current Operating Lease, Other Liability, Current Operating lease liabilities Operating Lease, Liability, Current Total operating lease liabilities Operating Lease, Liability Operating leases: Weighted average remaining lease term (years) Operating Lease, Weighted Average Remaining Lease Term Operating leases: Direct Financing Lease, Lease Income [Abstract] Weighted average discount rate Operating Lease, Weighted Average Discount Rate, Percent Intangible Assets Intangible Assets Disclosure [Text Block] Numerator: Net Income (Loss) Available to Common Stockholders, Basic [Abstract] Net loss Denominator: Weighted Average Number of Shares Outstanding Reconciliation [Abstract] Weighted-average number of shares-basic (in shares) Dilutive securities-equity awards (in shares) Incremental Common Shares Attributable to Dilutive Effect of Share-based Payment Arrangements Weighted-average number of shares-diluted (in shares) Net loss per share - basic (in dollars per share) Net loss per share - diluted (in dollars per share) Antidilutive securities excluded from computation of earnings per share Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount